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The biology is compelling enough to justify that careful engagement

8.1.1 Genomic and system-level approaches In the last two to three decades, NGS technologies have generated large amounts of omics data (genomics, transcriptomics, proteomics, epigenomics, and metabolomics), post-translational modification data (phosphorylation, SUMOylation, ubiquitinylation, etc.), single-cell, ATAC-Seq data and more, which provide a powerful lens for deciphering the molecular landscape of breast cancer (269)

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It is noteworthy that until recently, it had not been possible to develop an inhibitor towards RAS (147)